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Chicken Bubble Biscuit Bake Casserole – Easy Family Dinner Recipe

Make this creamy, cheesy Chicken Bubble Biscuit Bake Casserole in just 10 minutes of prep! A cozy, family-favorite dinner perfect for busy nights.
Prep Time 10 minutes
Cook Time 35 minutes
Total Time 44 minutes
Course Main Course
Cuisine American
Servings 7
Calories 410 kcal

Ingredients
  

  • 2 cups cooked chicken, shredded or diced (rotisserie recommended)
  • 1 (10.5 oz) can cream of chicken soup (or cream of mushroom/celery)
  • ½ cup our cream (or plain Greek yogurt for a lighter twist)
  • ½ cup milk
  • 1 cup frozen mixed vegetables (peas, carrots, corn, beans)
  • 1 tsp garlic powder
  • ½ tsp onion powder
  • ½ tsp paprika (optional, for color)
  • Salt and pepper, to taste
  • 1 (16 oz) can refrigerated biscuit dough, each biscuit cut into quarters
  • 1 cup shredded cheddar cheese (or mozzarella / Monterey Jack blend)
  • 1 tbsp melted butter (optional, for brushing)

Optional Add-ins:

  • ½ cup cooked bacon crumbles
  • 1 cup steamed broccoli florets
  • 1 tbsp ranch seasoning mix for extra zest

Instructions
 

  • Preheat the oven: Set your oven to 350°F (175°C). Lightly grease a 9x13-inch baking dish with nonstick spray or butter.
  • Mix the filling: In a large mixing bowl, stir together the cream of chicken soup, sour cream, milk, garlic powder, onion powder, paprika, salt, and pepper. Add the cooked chicken and vegetables. Stir until everything is evenly coated.
  • Add the biscuits: Open the can of refrigerated biscuits, cut each into quarters, and gently fold them into the creamy mixture. Coat every piece — this helps them bake up soft inside but golden on top.
  • Assemble the casserole: Pour the mixture into your prepared baking dish. Spread it out evenly and sprinkle cheese on top.
  • Bake to bubbly perfection: Cover with foil and bake for 20 minutes. Then uncover and bake another 10–15 minutes, until the biscuits are puffed, golden, and cooked through. If the top browns too fast, loosely tent with foil.
  • Finish and serve: Brush the top with melted butter if desired. Let it cool for 5 minutes before serving — it thickens slightly as it rests.